Skip to main content

Verified by Psychology Today

Health

Mind, Body and Election 2016

Our immune system is getting burned by this heated election.

Shutterstock
Source: Shutterstock

Judging by social media, the upcoming presidential election is very emotionally charged. These emotions threaten our health because the emotion areas of the brain are rich with receptors for neuropeptides (messenger molecules). These neuropeptides bring information from more than 50 of the body’s informational substances such as gut peptides, hormones, growth factor etc. [1, 2] This connects the brain, glands, and immune system and forms a network that expresses the emotional highs and lows of life at a cellular level, or nerdly speaking – the biochemical substrate of emotion.[3-6] This connectivity between the emotional centers of our brain and our immune system determines how well we can prevent or recover from disease based on the efficacy of communication via neuropeptides.[1, 2]

In human evolution neuropeptides and their receptors (host molecules) have been around since Day One.[7-9] We identified opiate peptides and insulin in unicellular organisms before the Beatles broke up.[7, 10-12] Take home message: neuropeptides have been used for intercellular communication between one-cell organisms. [13-15] Therefore, in complex organisms (that would be us) unique neuropeptide distributions are used to communicate emotion on a biochemical level.[1, 2, 16-23] Since evolution has preserved the structure and function of neuropeptides, then even the simplest organisms use neuropeptides to galvanize behaviors that have the greatest survival value.[2] In humans, it logically follows that the functional integration of the body’s cells via neuropeptide networks and their receptors is critical to survival, i.e., health and immune status. [2, 17]

Shutterstock
Source: Shutterstock

So the feelings generated by politics are expressed by neuropeptides in the emotional parts of the brain, which mediates communication to the other parts of our body such as our immune system. The integrity of this communication determines our ability to avoid and heal from disease. Picture an astronaut saying “Houston we have a problem,” and Houston not being able to hear the message.[1, 2, 16, 17, 23, 24]

This scenario on a cellular level increases the risk for colds and flus and vulnerability to chronic conditions such as Cardiac Disease, Diabetes, Multiple Sclerosis, Cancer, etc. [2, 16, 17, 25-33]

Soon, scientists will concede that separating psychology, neuroscience, endocrinology and immunology is an outdated approach; mind/body medicine is the scientific reality. Mounting research tells us that emotional status affects diseases we originally thought were completely somatic. I do not mean, “your attitude affects your recovery,” although most agree that is true. What research is finding is that your emotional state can dictate whether or not disease will occur in the body.[28, 29, 31, 33-47]

Shutterstock (altered by Dr. Gordon)
Source: Shutterstock (altered by Dr. Gordon)

That said, let's be candid -- this election is ugly. In addition, it is hard to be an American, because we are not Europe, Asia, Central or South America, Africa, Canada, or Australia – we are all of them. We do not practice Christianity, Islam, Judaism, Hinduism, Buddhism, Agnosticism or Atheism – we practice them all. America speaks many languages, has all levels of education, wealth, ability and disability. We are all that is good about humanity and all that is bad. We are all that is triumphant, and all that is tragic and sad.

So finding our way as a nation is very difficult – many rivers must be crossed to find some common higher ground. In political arenas many skirmishes must be fought over what to discard and what to cherish, as well as what to trumpet and what to silence.

Shutterstock
Source: Shutterstock

Humans are a social species, meaning in part, that membership in kinships, clans, and nations is vital because social relationships kept our ancestors alive. So naturally, where America is involved, emotions occur that will affect the neuropeptides that dictate our health status by affecting the efficacy of mind/body communication – particularly between the gut, the immune system, and the subcortical areas of the brain that regulate emotion.

And this affects everyone, even Americans who hate America, and claim not to care. Evolution appointed an inescapable biochemical need for social connectivity in all humans – for survival purposes. And at the end of the day, we are all just humans trying to survive. That and indifference, not hate, is the opposite of love – Hate is just love having a bad hair day. Remain fabulous and phenomenal.

Join my email list to receive notifications of new posts

Or visit me at:

Huffington Post

The Los Angeles Times

UCLA Center for the Neurobiology of Stress

Dr. Gordon online

Facebook

Twitter

References

1. Pert, C.B., H.E. Dreher, and M.R. Ruff, The psychosomatic network: foundations of mind-body medicine. Altern Ther Health Med, 1998. 4(4): p. 30-41.

2. Pert, C.B., et al., Neuropeptides and their receptors: a psychosomatic network. J Immunol, 1985. 135(2 Suppl): p. 820s-826s.

3. Pert, C., Molecules of Emotion. 1997, New York, New York: Scribner.

4. Pert, C.B. and S.H. Snyder, Properties of opiate-receptor binding in rat brain. Proc Natl Acad Sci U S A, 1973. 70(8): p. 2243-7.

5. Pert, C.B. and S.H. Snyder, Opiate receptor binding--enhancement by opiate administration in vivo. Biochem Pharmacol, 1976. 25(7): p. 847-53.

6. Pert, C.B., et al., Biochemical and autoradiographic evidence for type 1 and type 2 opiate receptors. Adv Biochem Psychopharmacol, 1980. 22: p. 581-9.

7. LeRoith, D., et al., Evolutionary origins of vertebrate hormones: material very similar to adrenocorticotropic hormone, beta-endorphin, and dynorphin in protozoa. Trans Assoc Am Physicians, 1981. 94: p. 52-60.

8. Roth, J., et al., Evolutionary origins of neuropeptides, hormones, and receptors: possible applications to immunology. J Immunol, 1985. 135(2 Suppl): p. 816s-819s.

9. Roth, J., et al., The evolutionary origins of hormones, neurotransmitters, and other extracellular chemical messengers: implications for mammalian biology. N Engl J Med, 1982. 306(9): p. 523-7.

10. LeRoith, D., et al., Insulin or a closely related molecule is native to Escherichia coli. J Biol Chem, 1981. 256(13): p. 6533-6.

11. LeRoith, D., J. Shemer, and C.T. Roberts, Jr., Evolutionary origins of intercellular communication systems: implications for mammalian biology. Horm Res, 1992. 38 Suppl 2: p. 1-6.

12. LeRoith, D., et al., Phylogeny of the insulin-like growth factors (IGFs) and receptors: a molecular approach. Mol Reprod Dev, 1993. 35(4): p. 332-6; discussion 337-8.

13. Seeger, T.F., et al., In vivo autoradiography: visualization of stress-induced changes in opiate receptor occupancy in the rat brain. Brain Res, 1984. 305(2): p. 303-11.

14. Quirion, R., et al., Phencyclidine (angel dust)/sigma "opiate" receptor: visualization by tritium-sensitive film. Proc Natl Acad Sci U S A, 1981. 78(9): p. 5881-5.

15. Olson, G.A., et al., Endogenous opiates: through 1978. Neurosci Biobehav Rev, 1979. 3(4): p. 285-99.

16. Vitetta, L., et al., Mind-body medicine: stress and its impact on overall health and longevity. Ann N Y Acad Sci, 2005. 1057: p. 492-505.

17. Szczepanska-Sadowska, E., et al., Brain and cardiovascular diseases: common neurogenic background of cardiovascular, metabolic and inflammatory diseases. J Physiol Pharmacol, 2010. 61(5): p. 509-21.

18. Skuse, D.H. and L. Gallagher, Genetic influences on social cognition. Pediatr Res, 2011. 69(5 Pt 2): p. 85R-91R.

19. Rothman, R.B., et al., Visualization of rat brain receptors for the neuropeptide, substance P. Brain Res, 1984. 309(1): p. 47-54.

20. Pert, C., Candace Pert: a molecular Jungian in search of the quantum experiment. Interview by Sheldon Lewis. Adv Mind Body Med, 2002. 18(1): p. 36-40.

21. Lugovic-Mihic, L., et al., Psychoneuroimmunologic aspects of skin diseases. Acta Clin Croat, 2013. 52(3): p. 337-45.

22. Fetissov, S.O. and P. Dechelotte, The new link between gut-brain axis and neuropsychiatric disorders. Curr Opin Clin Nutr Metab Care, 2011. 14(5): p. 477-82.

23. Burgdorf, J. and J. Panksepp, The neurobiology of positive emotions. Neurosci Biobehav Rev, 2006. 30(2): p. 173-87.

24. Pert, C.B., The wisdom of the receptors: neuropeptides, the emotions, and bodymind. 1986. Adv Mind Body Med, 2002. 18(1): p. 30-5.

25. Sajdyk, T.J., A. Shekhar, and D.R. Gehlert, Interactions between NPY and CRF in the amygdala to regulate emotionality. Neuropeptides, 2004. 38(4): p. 225-34.

26. Ohno, K. and T. Sakurai, Orexin neuronal circuitry: role in the regulation of sleep and wakefulness. Front Neuroendocrinol, 2008. 29(1): p. 70-87.

27. Laorden, M.L., et al., Hypothalamic orexin--a neurons are involved in the response of the brain stress system to morphine withdrawal. PLoS One, 2012. 7(5): p. e36871.

28. Solomon, G.F. and R.H. Moss, Emotions, Immunity, and Disease; a Speculative Theoretical Integration. Arch Gen Psychiatry, 1964. 11: p. 657-74.

29. Solomon, G.F. and A. Amkraut, [Emotions, immunity and disease]. Fiziol Cheloveka, 1984. 10(2): p. 242-51.

30. Weihs, K.L., et al., Negative affectivity, restriction of emotions, and site of metastases predict mortality in recurrent breast cancer. J Psychosom Res, 2000. 49(1): p. 59-68.

31. Southam, C.M., Emotions, immunology, and cancer: how might the psyche influence neoplasia? Ann N Y Acad Sci, 1969. 164(2): p. 473-5.

32. Morrison, R., Interrelationship of the mind, body and emotions in the cancer fight. Radiol Technol, 1990. 62(1): p. 28-31.

33. Kowal, S.J., Emotions as a cause of cancer; 18th and 19th century contributions. Psychoanal Rev, 1955. 42(3): p. 217-27.

34. Schafer, D.W., Pain, emotions, and the cancer patient. Surg Annu, 1984. 16: p. 57-67.

35. Lynch, H.T. and A.J. Krush, Heredity, emotions and cancer control. Postgrad Med, 1968. 43(2): p. 134-8.

36. Hirschfeld, A.H., Cancer and emotions. J Mich State Med Soc, 1961. 60: p. 497-9.

37. Salt, W., Irritable Bowel Syndrome and The Mind Body Connection. . 2002, Columbus, OH: Parkview Publsihing

38. Piko, B., [Correlations of health, happiness and wellbeing in modern society]. Lege Artis Med, 2014. 24(4): p. 229-33.

39. Park, L., et al., Innate immunity receptor CD36 promotes cerebral amyloid angiopathy. Proc Natl Acad Sci U S A, 2013. 110(8): p. 3089-94.

40. Pandya, D.P., V.H. Vyas, and S.H. Vyas, Mind-body therapy in the management and prevention of coronary disease. Compr Ther, 1999. 25(5): p. 283-93.

41. Ozgen, A.G., et al., Hypothalamus-hypophysis-thyroid axis, triiodothyronine and antithyroid antibodies in patients with primary and secondary Sjogren's syndrome. Clin Rheumatol, 2001. 20(1): p. 44-8.

42. Neary, N.M., C.J. Small, and S.R. Bloom, Gut and mind. Gut, 2003. 52(7): p. 918-21.

43. Mamtani, R. and R. Mamtani, Ayurveda and Yoga in Cardiovascular Diseases. Cardiol Rev, 2004. 12(5): p. 155-162.

44. Lopez-Ibor, J.J., T. Ortiz, and M.I. Lopez-Ibor, Perception, experience and body identity. Actas Esp Psiquiatr, 2011. 39 Suppl 3: p. 3-118.

45. Leslie, M., Weak of body, weak of mind? Dwindling testosterone concentrations in elderly men increase risk of Alzheimer's disease. Sci Aging Knowledge Environ, 2004. 2004(1): p. nf3.

46. Kropiunigg, U., Basics in psychoneuroimmunology. Ann Med, 1993. 25(5): p. 473-9.

47. Kabeya, Y., et al., Association Between Diabetes and Increased Prevalence of Paranasal Sinus Disease: A Cross-Sectional Study in Japanese Adults. J Epidemiol, 2015.

advertisement
More from Billi Gordon Ph.D.
More from Psychology Today