Genetics
Rethinking Diagnoses
A behavioral genetics approach to understanding disorder.
Posted April 26, 2023 Reviewed by Vanessa Lancaster
Key points
- Robert Plomin, a psychologist and behavioral geneticist, argues that mental disorders exist on a continuum rather than as discrete categories.
- A behavioral genetics perspective has significant implications for mental health treatment, suggesting a more personalized approach.
- Recognizing the quantitative nature of disorders might inform more effective interventions that address specific symptoms and needs.
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Robert Plomin, a psychologist and behavioral geneticist, has significantly contributed to psychology and psychiatry. In recent years, he has gained attention for his thought-provoking views on the nature of mental disorders, challenging the traditional diagnostic system used in psychiatry and psychology. His work focuses on understanding the genetic and environmental factors contributing to individual behavior and mental health differences.
Plomin's most contentious claim asserts that mental health practitioners' current understanding of mental disorders needs a complete overhaul. In his book, Blueprint: How DNA Makes Us Who We Are, Plomin asserts, "...disorders are the quantitative extreme of the same genetic factors that affect the rest of the distribution. Stated more provocatively, there are no common disorders, just quantitative traits—the abnormal is normal."
Mental Disorders as Quantitative Dimensions
Plomin's central argument is that mental disorders are not discrete categories but quantitative dimensions that exist on a continuum. He believes that psychiatric diagnoses, such as schizophrenia or depression, are arbitrary and do not reflect the true complexity of mental health. Instead, he suggests we should view mental health problems as a spectrum, with everyone falling somewhere on that spectrum.
This perspective on mental health disorders is grounded in the science of genetics and the heritability of behavioral traits, particularly in the study of single-nucleotide polymorphisms (SNPs) and polygenic variance. SNPs are genetic variations that occur when a single nucleotide (A, T, C, or G) changes DNA. These variations can affect gene function and increase an individual's susceptibility to certain diseases, including mental health disorders. However, rather than focusing on a single gene, Plomin emphasizes the importance of polygenic variance, which refers to the influence of multiple genes on a particular trait or behavior.
Research has shown that polygenic variance accounts for a significant proportion of the variation in mental health disorders indicating that mental health disorders are influenced by the combined effects of many genes rather than a single gene. This view supports Plomin's perspective that mental health disorders exist on a spectrum rather than as discrete categories.
Implications for Treatment
According to Plomin, viewing disorders as a continuum has significant implications for how we approach mental health and treatment. He argues that the current diagnostic system has held clinicians back by creating false distinctions between those with a disorder and those without. This, in turn, has led to a focus on finding a cure rather than alleviating symptoms. Rather than focusing on curing a disorder, we should focus on alleviating symptoms and improving overall well-being. This means taking a more holistic approach to mental health treatment that considers an individual's genetics, life experiences, and social context.
By recognizing the quantitative nature of mental health disorders, we can move away from the traditional one size fits all approach to treatment and develop more personalized interventions that address an individual's specific symptoms and needs. We can achieve this by focusing on symptom reduction rather than diagnosis and incorporating genetic and environmental factors into the treatment process.
Comorbidity and Quantitative Nature of Mental Health Disorders
Plomin's view of mental health disorders as existing on a spectrum rather than discrete categories also sheds light on the high rates of comorbidity between different mental health disorders. Comorbidity refers to the occurrence of two or more mental health disorders in the same individual. This phenomenon is quite common in the field of mental health and can complicate diagnosis and treatment planning. By recognizing the quantitative nature of mental health disorders, we can better understand mental health's complex and interconnected nature and develop more effective interventions that address the individual's specific symptoms and needs.
Moving Forward in Mental Health Treatment
Plomin's conceptualization proposes a personalized and comprehensive method for treating mental health that considers an individual's distinctive genetic and environmental factors. Acknowledging the quantitative aspect of mental health disorders can help us veer away from the traditional diagnostic model and cater to the patient's specific symptoms. This thought-provoking idea has initiated a significant discussion in the mental health field by urging us to critically examine our current diagnostic system and contemplate alternate approaches to mental health treatment.
By recognizing the quantitative nature of mental health disorders, we might be able to formulate more effective interventions that concentrate on alleviating symptoms and enhancing overall well-being, resulting in better outcomes for people struggling with mental health challenges.